Disabled groups are vulnerable to poverty. One of the contributing factors is the lack of independence persons with disabilities. There are still many disabled people who are displaced and experience obstacles in creativity and work. The efforts of the community and the government to protect the disabled are not just to give a certain amount of money, but to provide skills to the disabled so that they can create independence. One of the programs implemented to create diffable independence with effective communication through implementation of the creative center's diffable empowerment program. The aim of this study was to find out the implementation of empowerable creative center empowerment program, to find out the independence of diffables, and contribution of implementing a creative creative-enabled empowerment program to diffable independence. This study uses a case study method with a type of qualitative approach. The number of informants in this study were 26 people. Data collection techniques in the form of interviews, observation, and study documentation. The validity of the data is in the form of source triangulation and triangulation of data collection techniques. The results of the study indicate that the implementation of the empowerment programof creative centers contributes to the independence of diffables in form economic, social and spiritual aspects. The economic aspects are quite good although there are still some people with disabilities who do not get capital assistance in the form of sewing machines so they do not feel the contribution of this program. While the social aspects are quite good with the holding of the DCC workshop. The spiritual aspects of the diffable showed a change in the character of the disabled person. Keywords: Empowerment, Disability, Independence Program.